I really love this piece by Ed Barrett from Animade. What I enjoy is that even though the style is simple the animation really brings a lot of life and personality into the characters. That mashed up with some great sound design makes for a brilliant little story.
P.S. Here is another little sample of what Animade can do called "Ready Steady Bang - 30 Ways." A simple idea but a lot of fun to watch, and if you really like it there is an iPhone game to go along with it. Check it out here.